miércoles, 27 de febrero de 2019

Rachel Fuller Brown and Elizabeth Lee Hazen, Nystatin



 BIOGRAPHY:
Rachel Fuller Brown was born on the 23rd of November, 1898 in Springfield, Massachusetts. Her father was George Hamilton Brown, and her mother Annie Brown.


Resultado de imagen de rachel fuller brownShe was an American biochemist, she studied at Harvard University, Mount Holyoke College and at the University of Chicago. She got the degree on Physic and Chemistry in the year 1920.

In the year 1948 she started a project with Elisabeth Lee Hazen, this led to a discovery, they found an antibiotic called Nystatin. It´s the first fungicide against fungi applicable to humans. It´s useful in cutaneous and mucosa infections, produced by Candida Abbicons

Se died on die 14th of Junary 1980 in Albany, New York

Resultado de imagen de elizabeth lee hazenElizabeth was born on 24th of August, 1885 in Rich ( Mississippi). She died on the 24th of Juliy 1975. She became an orphan at the age of 3.

In 1931, she worked in the department of the state of New York, she found the sources of leukemia,She also founded the fungi that spoil poorly preserver food and how it works

At the department, she did studies of fungi and discovered treatments for fungal diseases.
INVETION:NYSTATIN
Resultado de imagen de nystatin wikipediaIt acts as fungistatic and fungicide, depending on the concetration. It binds to the sterols of the cell membrane of fungi, whoose spatial configuation disorganizes, which lets to an alteration of the permeability of the membrane with loss of amino-acids, purines and ions by the fungi, with alteration of cellular metabolism

https://en.wikipedia.org/wiki/Nystatin



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